Cowboy Bill’s Honky Tonk Saloon is the Southernmost Country Bar in the USA. Situated on Key West’s infamous Duval Street, Cowboy Bill’s is open seven days a week from 11 a.m. and never closes before 4 a.m.! Cowboy Bill's serves the best Mexican food on the island made from scratch every day. Our restaurant Salsa Loca uses traditional recipes and all fresh ingredients. The portions are huge, the cervesas are cold and the tequilla is flowing. Enjoy a real margarita made with any of the Tequilas on our Specialty Tequila Menu outside on the patio or inside the air conditioned sports bar. You can also call ahead for delivery or curbside pick up. We celebrate Happy Hour Monday through Friday from 4 pm to 7 pm with 2 fer 1 drink specials. Enjoy air-conditioning inside the Sports Bar while playing pool, darts, video games or watching some of our 27 TV’s. Kick back outside at the Saloon Bar while listening to great live music or boot scoot on the largest dance floor in Key West. Our newest addition is Miss Irene’s whiskey bar, featuring 30 unique whiskeys and bourbons from around the world. Giddy up on our saddle stools and overlook the whole bar. Our mechanical bull is bucking Tues-Sat from 10pm to 2 am. You can catch all the action on the bull or watch the musical performances on stage by logging onto our web cams. No honky tonk is complete without Pabst Blue Ribbon and our PBR’s are a buck everyday til 10 pm! (We're the number 1 retailer of PBR’s in South Florida.)